Muguruza, who beat Serena Williams in the final 12 months ago, walked off following the loss wagging her finger at the fans on Court Suzanne Lenglen.
A year after showing so much resolve while winning the French Open, Muguruza fell apart down the stretch.
She nearly pulled out of her first match but her condition improved afterwards, although the 24-year-old, who will be playing her first fourth-round match at Roland Garros, said her back is still stiff.
"The crowd today was a little bit tough on me, but I understand".
Garbine Muguruza did not take kindly to the way spectators pulled for her opponent - her French opponent, mind you - at the French Open.
Third seed Stan Wawrinka, the 2015 champion, faces a tricky match against Italian 28th seed Fabio Fognini and Japanese eighth seed Kei Nishikori is expected to advance at the expense of South Korea's Chung Hyeon.
Later in the interview, she spoke of her affection for the tournament and said she would look forward to returning, but also revealed the level of pressure she felt.
Beckham clears another hurdle in Miami MLS team bid
But Hardemon is skeptical as on that front well, adding: "I don't believe that, necessarily, a stadium will revitalize an area". The stadium would be the economic driver in the neighbourhood as Overtown is known to have endured economic difficulties.
"But when you go out there, this is something I don't want to think about and just fight with everything I have". A new Grand Slam victor is set to emerge at the tournament as none of the women's players remaining made that.
Mladenovic could have company in the quarterfinals, though: Frenchwoman Caroline Garcia plays her fourth-round match Monday.
For the second year in a row Williams has gone out to the Swiss in this stage of the tournament.
Williams, who turns 37 this month, earned all of those titles at Wimbledon or the U.S. Open. "It's a very painful defeat here in the French Open". Nadal skated by No. 17 Roberto Bautista Agut in straight sets, 6-1, 6-2, 6-2.
Here are the results from the men's singles tournament at Stade Roland Garros on Sunday, June 4.
Never mind the 16 double faults, Kristina Mladenovic downed defending champion Garbine Muguruza 6-1, 3-6, 6-3, sending the Roland Garros crowd into raptures as their darling reached the quarter-finals. Mladenovic won 6-1, 3-6, 6-3. "I just give her credit for playing well every point, even in the first set". Why is the King of Clay the No. 4 player in this tournament again?
Nadal, who turned 31 on Saturday, not only is chasing a record 10th title at Roland Garros, but also his 15th major overall, which would move him three shy of Federer's career record. Nadal won 6-0, 6-1, 6-0.
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