However, we anticipate a 2-0 victory for Jose Mourinho's men.
United only really had three clear opportunities in the first period, and two of those ended up in the back of the net as Palace's hopes of a positive result were all but ended ahead of the second 45 minutes.
One former Red Devils star was particularly impressed with him, as Phil Neville posted a hilarious series of tweets commemorating his impact on the game vs Palace. Marouane Fellaini (knock) is also unavailable.
Arriving into this one on the back of a trip to Russian Federation meant the Reds could perhaps have been forgiven for a sluggish start, but Mata had other ideas, as he tucked in Rashford's pull back after the young prodigy had turned Joel Ward inside out before handing it on a plate for the tricky playmaker to tuck home.
Bakary Sako, the winger pushed into service as a striker to replace Benteke, nearly equalised as he ran in from the left on to Andros Townsend's diagonal through ball, but goalkeeper David De Gea beat away the drive at his near post.
It was 3-0 four minutes after the interval though when Fellaini got his head to Rashford's curling free-kick as Palace defended the set-piece poorly.
Spanish worldwide David De Gea has been impressive so far this season and will likely keep his place in goal barring any injury. Martial squared the ball and found the evergreen Lukaku who tapped in to score United's fourth.
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United are yet to drop points at home this season, and it would be the biggest upset this season if they manage to do so against Palace - who are yet to score a goal this season and sit at the bottom of the table.
Subs not used: Romero, Bailly, Blind, Darmian. Rookie Freddie Ladapo is the only fit recognised forward Crystal Palace have.
Subs not used: Speroni, Kelly, Mutch, Lee. Conor Wickham and Wilfried Zaha will also miss out for Hodgson's side due to respective injuries.
Some may see Palace as an easy return to domestic action given they have suffered the worst start ever to a Premier League campaign.
The Red Devils are aiming to win the Premier League title this season after having finished sixth in the table under Mourinho last season. Let's hope it stays that way!
Recently it's been a long afternoon for whoever has played right-back against Manchester United, not least because they have to face Marcus Rashford for 60-plus minutes before a fresh-legged Anthony Martial enters the fray.
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